AC Milan vs Napoli Prediction, Preview, News, Odds: 28/9/2025 – Serie A

AC Milan host Napoli at the San Siro this Sunday in a fixture that promises drama, intensity, and tactical nuance. Both sides enter the contest in strong form, but differing approaches and key absences could define the outcome.

Milan’s Resurgence Under Allegri

Massimiliano Allegri’s second stint at Milan has started on a promising note. The Rossoneri sit third in Serie A with three victories from their opening four matches, and their attack looks increasingly fluid. Christian Pulisic has been central to that momentum, with his brace against Udinese underlining the American’s growing influence.

The anticipated debut of Christopher Nkunku adds further unpredictability to Milan’s forward line, offering versatility and creativity. Yet, not all news is positive—Rafael Leão remains sidelined, depriving Milan of their explosive winger, while midfield depth could be tested by injuries to Ardon Jashari and Santiago Giménez. Despite these concerns, Milan’s home record at the Meazza remains formidable, unbeaten in 32 of their last 40 fixtures and averaging over 20 attempts on goal per game.

Napoli’s Efficiency Under Conte

Napoli, guided by Antonio Conte, have been ruthless in their pursuit of a perfect start to the campaign. Four straight league wins showcase their resilience, with the 3-2 triumph over Pisa illustrating both attacking brilliance and defensive vulnerabilities.

Romelu Lukaku, who scored the decisive goal in their previous encounter with Milan, is unavailable, while Miguel Gutiérrez’s absence will likely force tactical adjustments in defense. Still, Napoli’s away form is impressive, boasting eight wins and six clean sheets across their last 15 road trips. Conte’s trademark discipline and emphasis on transitions could trouble Milan’s more possession-heavy style.

Key Battles and Historical Context

Historically, Napoli have often thrived at the San Siro, winning six of their last 12 visits. However, Milan’s current form at home is daunting, with Allegri’s men dominating possession and creating high-quality chances with consistency.

The midfield battle is expected to be decisive. Milan will lean on Pulisic and Youssouf Fofana to exploit Napoli’s defensive gaps, while the visitors will count on their structured pressing and counter-attacking ability to unsettle the Rossoneri. With Lukaku missing, Napoli may rely on Victor Osimhen’s pace and clinical finishing to lead the charge.

Prediction

Both teams bring strong form into this clash—each with five wins in their last six matches—but Napoli’s injury setbacks and Milan’s fortress-like home advantage tip the scales slightly toward the Rossoneri. A 2-1 victory for Milan feels likely, with Pulisic or Nkunku potentially delivering the decisive blow.

Prediction: AC Milan 2 – 0 Napoli

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